The kilometre is a unit of length and is a multiple of the metre; an SI derived unit. It has the symbol km.
A kilometre is equal to 1000m, 1094 yards and 0.621 miles.
Kilometres is used to measure road distances in the US, though the UK is still using the imperial "sister" miles.
The mile is a unit of length in the imperial unit system with the symbol mi.
It was originally an English unit but was adopted by many countries who all had their own slight variation on definition. The English mile, however, is equal to 63,360 inches, 5280 ft or 1760 yards.
The UK still uses the mile on all roadway signs rather than the kilometre; its SI "equivalent". It used to have the symbol 'm' until SI was established and it was changed to avoid confusion with the unit metre.